I am building a high throughput two-photon microscope for imaging large volumes of fixed tissue in-situ –as large as 1 cm3– with sub-micron resolution. This novel technology will be used to explore and understand the spatial organization of cells across scales. As part of this project, I have established a new Mesoimaging Laboratory at the MPI-CBG.
This project is carried on in close collaboration with the Zerial Lab. We aim to digitally reconstruct the entire mouse liver. For more information, check out their seminal work: "A versatile pipeline for the multi-scale digital reconstruction and quantitative analysis of 3D tissue architecture"